Polymeric Chitosan Nanoparticles as Antitumor for Human Breast Cancer Cell Lines

Polymeric Nanoparticles (NPs) were widely used in drug delivery, disease diagnosis, and/or treatment. Targeted delivery to cancer cells is a highly smart application of polymers NPs. Previous studies showed that chitosan NPs were represented as attractive for drug vector, gene delivery, and tumor gene delivery or treatment. In vitro cytotoxicity of chitosan and chitosan derivatives prepared NPs were determined as MTT assay, against different three types of human breast cancer cell lines which are BT cell lines, MCF-7 cell lines, and SKBR3 cell lines, and the cell proliferation of each type of breast cancer cell lines were appeared highly significant decreasing (p