Bilayer Tablet of Metoprolol Tartrate and Hydrochlorthiazide: a Novel Approach for Bilayer Tablet Formulation and Evaluation - Shrinivas Mohite - Books - LAP LAMBERT Academic Publishing - 9783659186684 - August 19, 2012
In case cover and title do not match, the title is correct

Bilayer Tablet of Metoprolol Tartrate and Hydrochlorthiazide: a Novel Approach for Bilayer Tablet Formulation and Evaluation

Shrinivas Mohite

Price
zł 215.90
excl. VAT

Ordered from remote warehouse

Expected delivery May 23 - Jun 5
Add to your iMusic wish list

Bilayer Tablet of Metoprolol Tartrate and Hydrochlorthiazide: a Novel Approach for Bilayer Tablet Formulation and Evaluation

The main goal of present study was to formulate and invitro evaluate bilayer tablets of Metoprolol tartrate and Hydrochlorothiazide. In this tablet hydrochlorothiazide was formulated as immediate release for which sodium starch glycolate and croscarmellose sodium was used as superdisintegrants. While metoprolol tartrate was formulated as sustained release for which HPMC K4 M and Eudragit RSPO were used as release retarding polymers. In this bilayer tablet hydrochlorothiazide showed quick action and the sustained release of metoprolol tartrate maintain the drug concentration within therapeutic range for period of 12 hrs. Prepared tablets were evaluated for thickness, hardness, friability, uniformity of weight, disintegration time and dissolution study. Disintegration time and drug release were taken as the basis to optimize the tablets.

Media Books     Paperback Book   (Book with soft cover and glued back)
Released August 19, 2012
ISBN13 9783659186684
Publishers LAP LAMBERT Academic Publishing
Pages 120
Dimensions 150 × 7 × 226 mm   ·   185 g
Language English