Fluoromethylation Reactions: Nucleophilic and Electrophilic Fluoromethylation Reactions and Related Chemistry

Fluorocarbon molecules possess unique properties that make them useful in various facets of life. More recently fluorine chemistry has had a major impact on the pharmaceutical industry and biomedicinal research. The importance of fluorinated molecules and fluorinated analogues of natural compounds is of growing interest to the scientific community because of the increased understanding of the importance of fluorine in pharmacological properties. It has triggered the need for developing new synthetic methodologies for the introduction of fluorine and fluoroalkyl groups into various organic molecules which will enable the scientific world to explore new fluoroorganics. This book covers novel nucleophilic monofluoromethylation reactions, synthesis of new electrophilic difluoromethylating reagents and their use in making novel difluoro methyl compounds. The book also details on the use of solid hydrogen peroxide reagents for ipso hydroxylation of aryl boronic acids as well as on the synthesis of monodisperse poly vinyl pyridine nanospheres by emulsifier free emulsion polymerization.